The first Hindu Kush Himalaya Science-Policy Forum was held from 13–14 November at the ICIMOD headquarters in Kathmandu, Nepal. With the theme ‘Actions to sustain a global asset’, the event – organized by the Ministry of Forests and Environment, Government of Nepal, and ICIMOD – brought together more than 125 participants from the Hindu Kush Himalayan (HKH) region and beyond. Representatives of think-tanks, senior experts, and high-level decision makers discussed the key findings of the Hindu Kush Himalaya Assessment, contributed to the ‘HKH Call to Action’, and charted a way forward for strengthening regional cooperation.