Climate change impacts ecosystem services and geological processes and has long-term effects on food security and livelihoods. These impacts are not gender-neutral and they pose an added challenge in achieving gender-equitable livelihood goals. Ample literature and project implementation experience suggest that the consequences of climate change are disproportionately borne by women. Nepal is one of the countries most vulnerable to climate risks. Mountain ecosystems and those communities who depend on them for their livelihoods and other services are especially sensitive to climate variability. Rural Nepal is in the midst of a complex period of transition involving out-migration, urbanisation and commercialisation of the local economy. Further, various vulnerability assessments suggest that the mountains of Nepal are highly vulnerable to climate change. Efforts to manage and restore natural environments can help people residing in these mountain ecosystems to adapt to a changing climate. A sound understanding of their adaptive capacity is therefore critical for effective adaptation measures on the ground. Thus, ecosystem-based approaches were piloted in the Panchase area of Nepal through the global “Ecosystems-based Adaptation (EbA) in Mountains” programme. In order to reduce the vulnerability of local communities and enhance ecosystem resilience, homestay business promotion was a key part of the EbA approach. Further, a set of EbA measures was implemented as part of the integrated approach. These measures helped to diversify livelihood opportunities and reduce the shocks and stresses of climate change. Women were able to participate more effectively and their ability to earn economic, social, cultural and environmental benefits was enhanced. This helped to improve gender resilience, as linked with the protection of different ecosystem services and the preservation of community culture.