This paper looks at the progress made in the implementation of the Convention on Biological Diversity (CBD) in the eight countries of the Hindu Kush-Himalayan region using the national reports to the CBD as the primary source. The draft paper was presented for comment at side events during the Fourteenth Meeting of the Subsidiary Body on Scientific, Technical, and Technological Advice in Nairobi, Kenya, and the Tenth Meeting of the Conference of the Parties to the CBD in Nagoya, Japan in 2010. The paper concludes that all the Hindu Kush-Himalayan countries are making efforts to prioritise conservation, but that they are at different stages of CBD implementation. Progressive conservation policies and legislation for management of biological resources in a participatory way have been developed which provide a strong basis for supporting CBD implementation in the region.