In the Himalaya, people live in widely spread settlements and suffer more from landslides than from any other type of natural disaster. The intense summer monsoons are the main factor in triggering landslides. However, the relations between landslides and slope hydrology have not been a focal topic in Himalayan landslide research. This paper deals with the contributing parameters for the rainfall-triggered landslides which occurred during an extreme monsoon rainfall event on 23 July 2002, in the south-western hills of Kathmandu valley, in the Lesser Himalaya, Nepal. Parameters such as bedrock geology, geomorphology, geotechnical properties of soil, and clay mineralogy are described in this paper. Landslide modeling was performed in SEEP/W and SLOPE/W to understand the relationship of pore water pressure variations in soil layers and to determine the spatial variation of landslide occurrence. Soil characteristics, low angle of internal friction of fines in soil, medium range of soil permeability, presence of clay minerals in soil, bedrock hydrogeology, and human intervention were found to be the main contributing parameters for slope failures in the region.