The city of Guwahati in north-east India falls under seismic zone V and is located in Assam gap of Himalaya. It has historically witnessed devastating earthquakes up to 8.7 on the Richter scale in 1897 and 1950. Unplanned rapid urbanization has increased its seismic vulnerability of life and property. This paper attempts to develop a ward-level hazard map of the city through systematic vulnerability analyses of the hazard by overlapping the ward map and the earthquake hazard microzonation map. Out of total 31 wards, five wards with highest density of population and taller buildings were taken as the most vulnerable areas and were selected for this study. These buildings have reinforced cement concrete framed structure but with various options of roof. A structured survey was carried out with Rapid Visual Screening (RVS) for existing building stock. Total100 buildings were randomly selected from the sample of residential, commercial, industrial, religious and mixed use buildings from municipal tax record. The buildings were categorized in terms of nine major vulnerability parameters based on Indian references. They were customized and graded as per US FEMA guideline which is more comprehensive in dealing with other building structures such as masonry or lightweight timber structures. Buildings under survey were scored and ranked based on their seismic vulnerability. Though the preliminary scoring passed (score>0.3) all buildings, but further refinement is needed to infer precisely. The result is helpful in formulating local level policy making to prioritize the building stock for appropriate remedial measures. The study also complements the earthquake resistant building codes and guidelinesof India developed for the new building construction.