The Karakoram-Pamir-Wakhan Landscape Conservation and Development Initiative (KPWLCDI) is a regional transboundary initiative to enhance cooperation between Afghanistan, China, Pakistan, and Tajikistan for biodiversity conservation and sustainable development in the western Hindu Kush Himalayas.
The landscape lies at the convergence of several important biogeographical regions and possesses a unique and rich assemblage of floral and faunal diversity. It has been listed as an important ecoregion and biodiversity hotspot by several international organizations. The region is also the source or upstream area of many important rivers, including the Amu Darya, Tarim River, and Indus River, and therefore has great conservation value.