The nature and causes of food and livelihood security in mountain areas are quite different to those in the plains. Rapid socioeconomic and environmental changes added to the topographical constraints have exacerbated the problem of food insecurity in the Hindu Kush-Himalayan (HKH) region. In Pakistan, food insecurity is significantly higher in the mountain areas than in the plains as a result of a range of biophysical and socioeconomic factors. The potential of mountain niche products such as fruit, nuts, and livestock has remained underutilized. Moreover, the opportunities offered by globalization, market integration, remittances, and non-farm income have not been fully tapped. This article analyzes the opportunities and challenges of food security in Pakistan?s mountain areas, and outlines a framework for addressing the specific issues in terms of four different types of area differentiated by agro-ecological potential and access to markets, information, and institutional services.