It is important that the Cartagena Protocol of the Convention on Biological Diversity recognizes that the impact of introducing GMOs could be gender-differentiated because men and women have different knowledges, needs and vulnerabilities. Women worldwide, and specially women from indigenous groups and local communities, need to have access to information, skills, equipment, regulatory frameworks and procedures. This will allow them to understand the issues, make informed decisions, manage, or avoid any potential risks associated to GMOs, have the capacity to implement the Protocol, and have an arena where their needs and concerns are heard and valued.