The Foundation for the Promotion and Investigation of Andean Products, PROINPA, is cutodian of the the Bolivian Andean tuber germplasm collection. Its focus has shifted from in situ conservation and resolving specific production constraints to promoting the sustainable use of Andean tubers in the contxt of a complex local social, economic and politican environment. PROINPA has joined the San Simon University in Cochabamba and other institutes in forming the Integrated Candelaria Project, PIC. Within PIC, realistic, interdisciplinary proposals for the sustainable use of biodiversity are being developed.